
U.S. Real World Evidence Solutions Market 2025 to Grow at 11.6 CAGR with 6.10 USD Billion Market Size: Analysis and Forecasts 2033
U.S. Real World Evidence Solutions Market by Type (Clinical Setting Data, Claims Data, Pharmacy Data, Patient Powered Data, Others), by End-user (Pharmaceutical, Medical Device Companies, Healthcare Payers, Healthcare Providers, Others), by Forecast 2025-2033
Key Insights
The U.S. Real World Evidence Solutions Market size was valued at USD 6.10 USD Billion in 2023 and is projected to reach USD 13.15 USD Billion by 2032, exhibiting a CAGR of 11.6 % during the forecast period. Real World Evidence (RWE) Solutions stand for the use of methodologies based on data from the real world to provide results concerning the safety, effectiveness, and economic impacts of medical applications. Examples include EHRs, patient registries, and wearable devices that will be the key source data. Functions contain the implementation of an information security policy, data processing, and international regulations. For example, applications can include comparative effectiveness research, post-raid 1 subgenera surgery syndrome withdrawal marking surveillance, and adjustments during therapy. The demand for RWE solutions in the USA is on the rise for their capacity to complement clinical trial data, increase research effectiveness, and make evidence-based decisions in healthcare all while satisfying regulatory requirements set out by the country.

U.S. Real-World Evidence Solutions Trends
- Increasing use of RWD in clinical research and regulatory decision-making
- Growing adoption of value-based care models
- Rising focus on patient-centricity
- Growing demand for personalized medicine
- Technological advancements in data collection and analysis
Driving Forces: What's Propelling the U.S. Real-World Evidence Solutions Market
- Increasing need for RWD to support regulatory decision-making: Regulatory agencies are increasingly requiring RWD to support new drug and device approvals, as well as label expansions.
- Rising adoption of value-based care models: Value-based care models reward providers for delivering high-quality care at a lower cost. RWD can be used to track patient outcomes and identify areas for improvement.
- Growing focus on patient-centricity: Patients are increasingly demanding a more personalized and patient-centered healthcare experience. RWD can be used to understand patient preferences and develop treatments that are tailored to their individual needs.
Challenges and Restraints in U.S. Real-World Evidence Solutions Market
- Data quality and integrity: RWD can be heterogeneous and inconsistent, which can pose challenges for data analysis and interpretation.
- Data privacy and confidentiality: RWD often contains sensitive patient information, which must be protected from unauthorized access and use.
- Lack of interoperability: RWD is often stored in different formats and systems, which can make it difficult to integrate and analyze.
Emerging Trends in U.S. Real-World Evidence Solutions
- Artificial intelligence (AI) and machine learning (ML): AI and ML are being used to develop new methods for collecting, analyzing, and interpreting RWD.
- Blockchain technology: Blockchain technology is being used to create secure and transparent systems for sharing RWD.
- Patient-generated data: Patient-generated data (PGD) is increasingly being used to supplement traditional sources of RWD.
Growth Catalysts in the U.S. Real-World Evidence Solutions Industry

- Government initiatives: The U.S. government is investing in RWE research and development, which is expected to drive the growth of the market.
- Industry collaborations: Pharmaceutical and medical device companies are partnering with RWE solution providers to develop new and innovative products and services.
- Growing demand for personalized medicine: The growing demand for personalized medicine is driving the need for RWD that can be used to develop tailored treatments for individual patients.
Leading Players in the U.S. Real-World Evidence Solutions Market
- IQVIA Inc. (U.S.)
- IBM (U.S.)
- Cognizant (U.S.)
- Syneos Health (U.S.)
- Oracle (U.S.)
- Optum Inc. (United Health Group) (U.S.)
- Flatiron Health (F. Hoffmann-La Roche) (U.S.)
- Thermo Fisher Scientific Inc. (U.S.)
- Parexel International Corporation (U.S.)
- SAS Institute Inc. (U.S.)
- Perkin Elmer Inc. (U.S.)
Significant Developments in the U.S. Real-World Evidence Solutions Sector
- May 2023: Flatiron Health expanded its RWE offerings to include scientific, analytical, and consulting services.
- March 2023: MediMergent announced the implementation of its digital clinical trials platform in national clinical trials.
- May 2021: Optum, Inc. and Bassett Healthcare Network entered into a strategic collaboration to provide advanced analytical and IT solutions aimed at improving patient experience.
Comprehensive Coverage U.S. Real World Evidence Solutions Market Report
- Market size and forecast
- Market drivers, challenges, and restraints
- Market segmentation and analysis
- Competitive landscape
- Industry trends and developments
- Growth catalysts
- Regional Insights
- Key company profiles
Regional Insight
The U.S. is the largest market for RWE solutions, accounting for over 50% of the global market. The growth of the market in the U.S. is driven by the increasing demand for RWD to support regulatory decision-making, the rising adoption of value-based care models, and the growing focus on patient-centricity.
DROCs
- Drivers:
- Increasing need for RWD to support regulatory decision-making
- Rising adoption of value-based care models
- Growing focus on patient-centricity
- Advancements in technology, including AI and machine learning, that facilitate the analysis of large and complex RWD datasets
- Restraints:
- Data quality and integrity
- Data privacy and confidentiality
- Lack of interoperability
- Limited patient engagement and participation in data collection and analysis
- Opportunities:
- Artificial intelligence (AI) and machine learning (ML)
- Blockchain technology
- Patient-generated data
- Collaboration between healthcare providers, researchers, and technology companies to improve data quality and interoperability
- Challenges:
- Government regulation and compliance
- Competition from traditional data sources, such as clinical trials and electronic health records (EHRs)
- Addressing ethical concerns terkait with data privacy and patient consent
Pricing Analysis
The pricing of RWE solutions varies depending on the type of data, the size of the study, and the complexity of the analysis. However, the average cost of an RWE study is between USD 100,000 and USD 1 million.
Import And Export Analysis
The U.S. is a net importer of RWE solutions. The major import sources include the European Union, Canada, and Japan.
Segmentation
Type:
- Clinical Setting Data
- Claims Data
- Pharmacy Data
- Patient Powered Data
- Others
End-user:
- Pharmaceutical and Medical Device Companies
- Healthcare Payers
- Healthcare Providers
- Others
Patent/Trademark Analysis
There are a number of patents and trademarks related to RWE solutions. These include patents for methods of collecting, analyzing, and interpreting RWD, as well as trademarks for RWE solution products and services.
U.S. Real World Evidence Solutions Market REPORT HIGHLIGHTS
Aspects | Details |
---|---|
Study Period | 2019-2033 |
Base Year | 2024 |
Estimated Year | 2025 |
Forecast Period | 2025-2033 |
Historical Period | 2019-2024 |
Growth Rate | CAGR of 11.6% from 2019-2033 |
Segmentation |
|
Frequently Asked Questions
- 1. Introduction
- 1.1. Research Scope
- 1.2. Market Segmentation
- 1.3. Research Methodology
- 1.4. Definitions and Assumptions
- 2. Executive Summary
- 2.1. Introduction
- 3. Market Dynamics
- 3.1. Introduction
- 3.2. Market Drivers
- 3.2.1. Increasing Usage of Real World Evidence Solutions by Biopharmaceutical Companies to Propel the Demand for Preventive Products
- 3.3. Market Restrains
- 3.3.1. Challenges Associated with Data Quality and Privacy to Hinder Market Growth
- 3.4. Market Trends
- 3.4.1. Increasing Adoption of Value Based Healthcare
- 4. Market Factor Analysis
- 4.1. Porters Five Forces
- 4.2. Supply/Value Chain
- 4.3. PESTEL analysis
- 4.4. Market Entropy
- 4.5. Patent/Trademark Analysis
- 5. U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 5.1. Market Analysis, Insights and Forecast - by Type
- 5.1.1. Clinical Setting Data
- 5.1.2. Claims Data
- 5.1.3. Pharmacy Data
- 5.1.4. Patient Powered Data
- 5.1.5. Others
- 5.2. Market Analysis, Insights and Forecast - by End-user
- 5.2.1. Pharmaceutical
- 5.2.2. Medical Device Companies
- 5.2.3. Healthcare Payers
- 5.2.4. Healthcare Providers
- 5.2.5. Others
- 5.3. Market Analysis, Insights and Forecast - by Region
- 5.3.1.
- 5.1. Market Analysis, Insights and Forecast - by Type
- 6. Northeast U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 7. Southeast U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 8. Midwest U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 9. Southwest U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 10. West U.S. Real World Evidence Solutions Market Analysis, Insights and Forecast, 2019-2031
- 11. Competitive Analysis
- 11.1. Market Share Analysis 2024
- 11.2. Company Profiles
- 11.2.1 IQVIA Inc. (U.S.)
- 11.2.1.1. Overview
- 11.2.1.2. Products
- 11.2.1.3. SWOT Analysis
- 11.2.1.4. Recent Developments
- 11.2.1.5. Financials (Based on Availability)
- 11.2.2 IBM (U.S.)
- 11.2.2.1. Overview
- 11.2.2.2. Products
- 11.2.2.3. SWOT Analysis
- 11.2.2.4. Recent Developments
- 11.2.2.5. Financials (Based on Availability)
- 11.2.3 Cognizant (U.S.)
- 11.2.3.1. Overview
- 11.2.3.2. Products
- 11.2.3.3. SWOT Analysis
- 11.2.3.4. Recent Developments
- 11.2.3.5. Financials (Based on Availability)
- 11.2.4 Syneos Health (U.S.)
- 11.2.4.1. Overview
- 11.2.4.2. Products
- 11.2.4.3. SWOT Analysis
- 11.2.4.4. Recent Developments
- 11.2.4.5. Financials (Based on Availability)
- 11.2.5 Oracle (U.S.)
- 11.2.5.1. Overview
- 11.2.5.2. Products
- 11.2.5.3. SWOT Analysis
- 11.2.5.4. Recent Developments
- 11.2.5.5. Financials (Based on Availability)
- 11.2.6 Optum Inc. (United Health Group) (U.S.)
- 11.2.6.1. Overview
- 11.2.6.2. Products
- 11.2.6.3. SWOT Analysis
- 11.2.6.4. Recent Developments
- 11.2.6.5. Financials (Based on Availability)
- 11.2.7 Flatiron Health (F. Hoffmann-La Roche) (U.S.)
- 11.2.7.1. Overview
- 11.2.7.2. Products
- 11.2.7.3. SWOT Analysis
- 11.2.7.4. Recent Developments
- 11.2.7.5. Financials (Based on Availability)
- 11.2.8 Thermo Fisher Scientific Inc. (U.S.)
- 11.2.8.1. Overview
- 11.2.8.2. Products
- 11.2.8.3. SWOT Analysis
- 11.2.8.4. Recent Developments
- 11.2.8.5. Financials (Based on Availability)
- 11.2.9 Parexel International Corporation (U.S.)
- 11.2.9.1. Overview
- 11.2.9.2. Products
- 11.2.9.3. SWOT Analysis
- 11.2.9.4. Recent Developments
- 11.2.9.5. Financials (Based on Availability)
- 11.2.10 SAS Institute Inc. (U.S.)
- 11.2.10.1. Overview
- 11.2.10.2. Products
- 11.2.10.3. SWOT Analysis
- 11.2.10.4. Recent Developments
- 11.2.10.5. Financials (Based on Availability)
- 11.2.11 Perkin Elmer Inc. (U.S.)
- 11.2.11.1. Overview
- 11.2.11.2. Products
- 11.2.11.3. SWOT Analysis
- 11.2.11.4. Recent Developments
- 11.2.11.5. Financials (Based on Availability)
- 11.2.1 IQVIA Inc. (U.S.)
- Figure 1: U.S. Real World Evidence Solutions Market Revenue Breakdown (USD Billion, %) by Product 2024 & 2032
- Figure 2: U.S. Real World Evidence Solutions Market Share (%) by Company 2024
- Table 1: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Region 2019 & 2032
- Table 2: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Type 2019 & 2032
- Table 3: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by End-user 2019 & 2032
- Table 4: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Region 2019 & 2032
- Table 5: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Country 2019 & 2032
- Table 6: Northeast U.S. Real World Evidence Solutions Market Revenue (USD Billion) Forecast, by Application 2019 & 2032
- Table 7: Southeast U.S. Real World Evidence Solutions Market Revenue (USD Billion) Forecast, by Application 2019 & 2032
- Table 8: Midwest U.S. Real World Evidence Solutions Market Revenue (USD Billion) Forecast, by Application 2019 & 2032
- Table 9: Southwest U.S. Real World Evidence Solutions Market Revenue (USD Billion) Forecast, by Application 2019 & 2032
- Table 10: West U.S. Real World Evidence Solutions Market Revenue (USD Billion) Forecast, by Application 2019 & 2032
- Table 11: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Type 2019 & 2032
- Table 12: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by End-user 2019 & 2032
- Table 13: U.S. Real World Evidence Solutions Market Revenue USD Billion Forecast, by Country 2019 & 2032
Aspects | Details |
---|---|
Study Period | 2019-2033 |
Base Year | 2024 |
Estimated Year | 2025 |
Forecast Period | 2025-2033 |
Historical Period | 2019-2024 |
Growth Rate | CAGR of 11.6% from 2019-2033 |
Segmentation |
|
STEP 1 - Identification of Relevant Samples Size from Population Database



STEP 2 - Approaches for Defining Global Market Size (Value, Volume* & Price*)

Note* : In applicable scenarios
STEP 3 - Data Sources
Primary Research
- Web Analytics
- Survey Reports
- Research Institute
- Latest Research Reports
- Opinion Leaders
Secondary Research
- Annual Reports
- White Paper
- Latest Press Release
- Industry Association
- Paid Database
- Investor Presentations

STEP 4 - Data Triangulation
Involves using different sources of information in order to increase the validity of a study
These sources are likely to be stakeholders in a program - participants, other researchers, program staff, other community members, and so on.
Then we put all data in single framework & apply various statistical tools to find out the dynamic on the market.
During the analysis stage, feedback from the stakeholder groups would be compared to determine areas of agreement as well as areas of divergence
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