U.S. Sickle Cell Disease Treatment Market 2024-2032 Overview: Trends, Competitor Dynamics, and Opportunities

Key Insights

The U.S. Sickle Cell Disease Treatment Market is projected to reach USD 2.5 Billion by 2028, exhibiting a CAGR of 17.3% during the forecast period (2022-2028). This growth can be attributed to the rising prevalence of sickle cell disease, the introduction of new and improved treatment options, and the increasing awareness of the condition. The sickle Cell Disease (SCD) treatment sphere has empowered a combination of symptom-relieving approaches and potential cure options. Traditional approaches comprise medications around pain relief, collectively termed "analgesics," and fluid composition, called "hydration. "Hydroxyurea, the FDA-approved drug, lessens the symptoms and complications. Unlike many other cancer treatments, bone marrow transplant provides a cure option for patients which is however the case with considerable risk. Genetic engineering specifically gene therapy and gene editing seem to be the most promising for disease-modifying treatment in the long term as this method tackles the roots of SCD. In the US market, there's a trend towards personalized medicine and innovative therapies, with more and more investments in the development of new technologies and drugs that aim to improve the quality of life and the outcomes of the patients.

U.S. Sickle Cell Disease Treatment Trends

• Growing prevalence of sickle cell disease
• Increasing awareness of the condition
• Introduction of new and improved treatment options
• Government initiatives to support research and development of sickle cell disease treatments

Driving Forces: What's Propelling the U.S. Sickle Cell Disease Treatment Market

• Rising prevalence of sickle cell disease: The number of individuals living with sickle cell disease is increasing due to factors such as improved screening and diagnosis, as well as increased life expectancy.
• Introduction of new and improved treatment options: Advancements in research have led to the development of several new and improved treatments for sickle cell disease, including targeted therapies, stem cell transplants, and gene therapies.
• Government initiatives to support research and development: Government agencies, such as the National Institutes of Health (NIH) and the Food and Drug Administration (FDA), provide funding and support for research aimed at discovering new and more effective treatments for sickle cell disease.
• Growing awareness of the condition: Increased awareness of sickle cell disease among healthcare providers, patients, and the general public has led to a greater emphasis on early diagnosis, comprehensive care, and improved outcomes.
• Increasing demand for curative therapies: Patients and their families are increasingly seeking curative therapies for sickle cell disease, which offer the potential for a long-term or permanent solution to the condition.

Challenges and Restraints in U.S. Sickle Cell Disease Treatment Market

• High cost of treatment
• Lack of access to specialized care
• A limited number of approved treatment options
• Complexities associated with disease management

Emerging Trends in U.S. Sickle Cell Disease Treatment

• Development of gene therapy and stem cell transplantations
• Use of hydroxyurea and other disease-modifying therapies
• Growing focus on patient-centered care
• Use of artificial intelligence and machine learning to improve diagnosis and treatment

Growth Catalysts in the U.S. Sickle Cell Disease Treatment Industry

• Rising prevalence of sickle cell disease
• Introduction of new and improved treatment options
• Government initiatives to support research and development of sickle cell disease treatments
• Growing awareness of the condition

Market Segmentation: U.S. Sickle Cell Disease Treatment Analysis

Treatment Modality:

• Bone Marrow Transplant
• Blood Transfusion
• Pharmacotherapy
• Hydroxyurea
• Branded Products:
  • Endari
  • Adakveo
  • Oxbryta
  • Zynteglo
  • PYRUKYND (Mitapivat)

End-user:

• Hospitals
• Specialty Clinics
• Others

Leading Players in the U.S. Sickle Cell Disease Treatment Market

• Bristol-Myers Squibb Company (U.S.) 
• Novartis AG (Switzerland) 
• Global Blood Therapeutics, Inc. (Pfizer Inc.) (U.S.) 
• Emmaus Medical, Inc. (U.S.) 
• Bluebird Bio Inc. (U.S.) 
• Agios Pharmaceuticals, Inc. (U.S.) 

Significant Developments in the U.S. Sickle Cell Disease Treatment Sector

• August 2022 – Bluebird Bio Inc. received U.S. Food and Drug Administration (FDA) approval for ZYNTEGLO for the treatment of beta‑thalassemia in adult and pediatric patients.
• August 2019 – Emmaus Medical, Inc. partnered with Oncology Supply for the distribution of Endari.
• March 2019 – Emmaus Medical, Inc. signed an agreement with Express Scripts, a pharmacy benefits manager (PBM). This agreement ensured that patients in need had access to Emmaus's Endari.

Comprehensive Coverage U.S. Sickle Cell Disease Treatment Market Report

• Market Overview
• Market Dynamics
• Market Segmentation
• Competitive Landscape
• Industry Analysis
• Regional Analysis
• Future Outlook

Pricing Analysis

• Pricing Analysis by Region
• Pricing Analysis by Company
• Pricing Analysis by Treatment Modality

Import And Export Analysis

• Import and Export Analysis by Region
• Import and Export Analysis by Country
• Import and Export Analysis by Port

Segmentation

• Market Segmentation by Treatment Modality
• Market Segmentation by End-user
• Market Segmentation by Region

Patent/Trademark Analysis

• Patent Analysis by Company
• Trademark Analysis by Company